Impact of multinucleated blastomeres on embryo developmental competence, morphokinetics, and aneuploidy
نویسندگان
چکیده
منابع مشابه
the effect of e-64 on the developmental competence of sheep cocs during in vitro maturation
in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.
Impact of the presence of one or more multinucleated blastomeres on the developmental potential of the embryo to the blastocyst stage.
A retrospective study of 5,982 embryos in 619 blastocyst-stage embryo transfer cycles revealed that detection of multinucleated blastomeres either on day 2 or 3 signifies a poor prognosis for blastocyst formation and that no good-quality blastocyst can be expected from an embryo with more than one multinucleated blastomere. Patients should be counseled regarding a poor prognosis when multiple e...
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The presence of multinucleated blastomeres (MNBs) in embryos is associated with poor developmental competence in assisted reproductive technologies. This phenomenon is observed not only in humans but also in other animal species. The purpose of the present study was to investigate the characteristics of embryos with MNBs (MNB embryos) that could be utilized in embryo transfer. The developmental...
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Sir, We have read the article published in your journal by Taylor et al. (2014) with much interest. In this review the authors properly summarize the mechanisms, origins and incidence of chromosomal mosaicism in humans. The review is rigorous, exhaustive and very well-documented, and therefore we congratulate the authors for their work. Nevertheless, we find that some relevant information about...
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Oocyte development is the end result of a sophisticated biological process that is hormonally regulated and produced by highly specialized cellular lines that differentiate in early embryo/fetal development. Embryo development is initially regulated by maternal transcripts until replaced by embryonic genomic expression. Then, an assortment of hormones and local environmental factors in various ...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2016
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2016.04.041